Humanin

Product Name: Humanin
Scientific Name: Mitochondrial-Derived Peptide Humanin (MT-RNR2 Peptide)
Synonyms: HN, MAPRGFSCLLLLTSEIDLPVKRRA
Sequence: MAPRGFSCLLLLTSEIDLPVKRRA
CAS Number: 330936-69-1
Molecular Formula: C₁₁₉H₂₀₄N₃₄O₃₂S₂
Molecular Weight: ~2685 Da

Description:
Humanin is a small, naturally occurring 24–amino acid peptide encoded within the mitochondrial genome (MT-RNR2). First discovered in 2001, it has been studied for its potential roles in cellular stress responses, mitochondrial signaling, and neuroprotective mechanisms.

Research Notes:

• Encoded in the mitochondrial 16S rRNA gene.

• Interacts with receptor complexes such as CNTFR/WSX-1/gp130.

• Investigated for effects in oxidative stress, metabolic regulation, and neuroprotection.

• Frequently used in in-vitro and in-vivo research models.

• Highly stable when stored as lyophilized powder at -20 °C.

Form: Lyophilized powder, ≥98% purity (HPLC).

Storage Guidelines:

• Lyophilized: Store at -20 °C, protect from light/moisture.

• Reconstituted: Store at 2–8 °C, avoid freeze-thaw cycles.

Disclaimer:
For research use only. Not for human consumption, medical, or veterinary use. These statements have not been evaluated by the FDA.